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Keimyung Medical Journal 1990;9(4):488-492.
A Case of Borderline Tuberculoid Leprosy with Type 1 Reaction
1형 나반응을 동반한 근결핵양나 1례
노용지; 최윤애; 이규석; 송준영
Abstract
Reactions are acute or subacute hypersensitivity states that complicated the existing active and; more often; the treated infection. A modern description of reactions in Hansen's disease will include 3 types such as Type 1 reaction; erythema nodosum leprosum; and Lucio's phenomenon. Type 1 reaction occurs in patients suffering from borderline leprosy during the first six months of treatment. Characteristic symptoms are nerve pain concomittently with muscle paralysis; rapid swelling & erythema of some or all of the skin lesions and edema of face; hands & feet. It is generally considered that this type of reaction is a delayed hypersensitivity phenomenon in which antigen from breaking down bacilli reacts with T lymphocytes. Our case was sixty five year old woman who had multiple erythematous; swollen lesions on the both hands; feet and face; and suffered from paresthesia; dyshydrosis and mild tenderness on that sites 1 year ago. The symptoms were more aggrevated 20 days ago. General symptoms were accompanied such as fever; malaise; fatigue; loss of appetite. Family and past history was non contributory. And we tried many tests; skin smear and skin biopsy and then concluded final diagnosis was borderline tuberculoid leprosy with type 1 reaction. We had treated this patient with 20-40mg of prednisolone; lOOmg of dapsone; 200mg of clofazimine and 600mg of rifampicin daily for a week; and then; had transfered to special leprosy clinic in the mild improved state. Now we present a case of borderline tuberculoid leprosy with type 1 reaction with references.
Key Words: Leprosy, Type 1 reaction
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