Rapidly Evolving Bilateral Ophthalmoplegia as an Initial Manifestation of Myasthenia |
급격히 진행하는 양안의 안근 마비로 발현한 중증근무력증 환자 |
이창엽; 전지예; 이병찬; 이형; 임정근; 김현아 |
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Abstract |
Myathenia gravis is an autoimmune neuromuscular disease leading to fluctuating muscle
weakness and fatigue. Symptoms are caused by circulating antiboties that block acetylcholine
receptor at the post synaptic neuromuscular juction; inhibiting the excitatory effects of the
neurotransmitter acetylcholine on receptor. At early stage of myasthenia gravis; ptosis and
diplopia are common symptoms. The ophthalmoplegia is a rare symptom of the early stage of
myasthenia gravis. We described a 52-year-old female with myasthenia gravis; presenting with
acute ophthalmoplegia. Within 3 weeks the patient was transferred to intensive care unit because
of respiratory failure. Thus; we have to consider that acute ophthalmolegia can be the initial
symptom of myasthenia gravis and disease course is rapidly deteriorated. |
Key Words:
Acute ophthalmoplegia,
Myasthenia gravis |