| Comparison of Thrombocytosis; Erythrocyte Sedimentation Rate and C-reactive Protein as
Prognostic Factors in Patients with Renal Cell Carcinoma |
| 신세포암에서 예후 인자로 혈소판 증가증; 적혈구침강속도 및 C반응단백의 비교 |
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서경원; 장혁수; 김병훈; 박철희; 김천일 |
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| Abstract |
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The purpose of this study was to assess relationship between the prognosis of patients and the
degree of erythrocyte sedimentation rate (ESR); C-reactive protein (CRP); and thrombocytosis
on the patients who underwent radical nephrectomy. The subject of study was 65 patients who
underwent radical nephrectomy with Renal cell carcinoma (RCC) and whose level of ESR; CRP and
thrombocytosis were measured at the time of making diagnosis. The study was conducted by
classifying above ESR 20 mm/hr; CRP 0.5 mg/dL and thrombocytosis 350;000/uL as "increased
group" and below these as "normal group". The tumor size; cellular type; pathologic stage; nuclear
grade and distant metastasis were compared between two groups. The thrombocytosis and ESR
were not found significant as prognostic factors in the multivariate analysis; but CRP was
associated with cellular type (p=0.022); high degree of nuclear grade (p=0.006) and distant
metastasis (p=0.001) and also was a significantly independent prognosis factor (p=0.020) in the
multivariate analysis. In conclusion; the measurement of CRP at the time of making diagnosis will
be very helpful for the estimation of prognosis in patients with RCC. |
| Key Words:
C-reactive protein, prognosis, renal cell carcinoma |
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