| CT-guided High-dose Percutaneous Ethanol Injection Therapy for Treatment of Bone
Metastasis of Hepatocellular Carcinoma: Preliminary Experience |
| 간세포암의 골 전이의 치료에 전산화 단층촬영 유도 하의 고 용량의 경피적 에탄올 주입술의 이용: 예비보고 |
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| Abstract |
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With the improved prognosis of patients with hepatocellular carcinoma (HCC); the
likelihood of diagnosing bone metastasis has increased. We evaluated the feasibility and safety of
percutaneous ethanol injection (PEI) therapy for treatment of bone metastasis of HCC. Between
March 2006 and April 2007; computed tomography (CT)-guided high-dose PEI therapy was
performed for six bone metastases (two ilium; one clavicle; one lumbar spine; one pubic bone; and
one ischium) in six patients with HCC. Follow-up CT scan was performed at 3-month intervals to
assess local recurrence. Feasibility of PEI therapy and complications associated with PEI therapy
were evaluated. A total of 12 sessions of PEI were performed for six bone metastases. Apparent
tumor necrosis was noted at CT scan performed 1 day and 1 month after PEI therapy in all six
bone metastases. During CT follow-up (range; 1 to 13 months; mean; 6.2 months); local
recurrence was not seen in all bone metastases. We did not experience any complication except
pain or fever during and/or after the procedure. PEI therapy was successfully performed for six
bone metastases in six patients with HCC. This therapy seems to be feasible and safe for
treatment of bone metastasis of HCC. |
| Key Words:
Alcohol ablation, Bone metastasis, Hepatocellular carcinoma |
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