| Short-Term Clinical Benefit of Sirolimus-Eluting
Stents Compared to Bare Metal Stents for Patients with
Acute Myocardial Infarction |
| Short-Term Clinical Benefit of Sirolimus-Eluting
Stents Compared to Bare Metal Stents for Patients with
Acute Myocardial Infarction |
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이상훈; 김권배; 남창욱; 허승호; 조윤경; 한성욱; 김윤년; 김기식; 이영수 |
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| Abstract |
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Sirolimus-eluting stents (SES) have been recently proven to reduce restenosis and
reintervention compared with bare metal stents (BMS). However; the effectiveness of SES in
acute myocardial infarction (AMI) remains uncertain. The aim of this study was to evaluate the
efficacy of SES implantation in patients with AMI compared with that of BMS. From January 2003
to April 2004; angioplasty with SES was performed in 76 patients (82 lesions) with AMI and the
result was compared with that of 106 patients (113 lesions) treated with BMS. The incidence of
major adverse cardiac events (death; nonfatal myocardial infarction; and target lesion
revascularization) and binary angiographic restenosis were evaluated. Antiplatelet therapies
included aspirin with clopidogrel; or cilostazole. follow-up angiography was performed at sixth
month. Baseline demographic characteristics and the incidence of short term adverse events were
similar between both SES and BMS groups. At follow-up angiography; SES group showed the
significantly lower incidences in adverse events (8.2% vs. 39.3%; p<0.01). late loss (0.38 ± 0.54
mm vs 1.34 ± 0.96 mm; p<0.01) and restenosis (5.9% vs. 35.6%; p<0.01) comparing to BMS
group. Therefore; SES implantation could be a safe and effective strategy for the treatment in
patients with AMI. |
| Key Words:
Acute myocardial infarction, Angioplasty, Sirolimus-eluting stent |
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