Effects of Alkalinized Intra-cuff Lidocaine on Postoperative
Airway Complaints Following Cesarean Section |
Effects of Alkalinized Intra-cuff Lidocaine on Postoperative
Airway Complaints Following Cesarean Section |
이용철; 신용섭; 홍지희; 김애라; 장영호
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Abstract |
Many reports have described postoperative airway complaints after endotracheal
intubation for general anesthesia; however; none have addressed cesarean sections. We
investigated the incidence and severity of postoperative airway complaints in pregnant women
receiving elective general anesthesia and evaluated the effect of intratracheal cuff lidocaine
administration on these complaints. Two hundred and ninety-four pregnant women undergoing
elective cesarean sections under general anesthesia; with American Society of Anesthesiologists
physical status ratings Ⅰ or Ⅱ; were randomly assigned to the two groups having endotracheal
tube cuffs inflated with either air (group A; mean volume = 6.4 ± 1.8 mL) or alkalinized lidocaine
(group L; mean volume = 6.2 ± 1.5 mL) (n = 147 in each group). Alkalinization of lidocaine was
achieved by the addition of 8.4% NaHCO3 to a 1:10 ratio of lidocaine:NaHCO3. The incidence and
severity of postoperative sore throat (POST); hoarseness; and coughing were evaluated during
the 24 hours immediately following cesarean sections. The incidence of POST; hoarseness; and
coughing were decreased in the group L (67.3%; 53.7%; and 9.5%; respectively) compared to the
group A (78.9%; 69.4%; and 19%; respectively) (p=0.025; 0.006; and 0.02; respectively). Intracuff
lidocaine significantly attenuated the severity of hoarseness. There was no significant
difference in Apgar scores in neonates between the two groups. Intra-cuff lidocaine effectively
decreased the incidence and severity of postoperative airway complaints in pregnant women
undergoing cesarean sections without affecting fetal outcome. |
Key Words:
cesarean section, hoarseness, lidocaine, postoperative complaints, sore throat |
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