A Case of 
Hemophagocytic Syndrome as the Initial Presentation of Systemic Lupus Erythematosus

Keimyung Medical Journal 2004;23(1):41-46.

A Case of Hemophagocytic Syndrome as the Initial Presentation of Systemic Lupus Erythematosus

전신성홍반성낭창의 첫 임상양상으로 발현된 혈구탐식증후군 1례

이완석; 김소연; 우창민; 신진향; 김영섭; 김지영; 서정현; 안동직; 배성화; 류헌모; 김상경

Abstract

Hemophagocytic syndrome (HPS) is a clinicopathological entity characterized by proliferation and activation of histiocytes with prominent hemophagocytosis in various organs; including bone marrow; and manifests clinically with high grade fever; cytopenia; hepatosplenomegaly; liver dysfunction and coagulopathy. Many diseases have been reported to be associated with this syndrome; particularly infection and malignant lymphoma. Here; we present a case of systemic lupus erythematosus (SLE) complicated by HPS; and the case was successfully treated with corticosteroid.

Key Words: Fever, Hemophagocytic syndrome, Pancytopenia, Systemic lupus erythematosus