Treatment of Acute Migraine with Subcutaneous Sumatriptan

Keimyung Medical Journal 1998;17(1):43-48.

급성 편두통에 대한 피하용 Sumatriptan의 효과

임정근; 이형; 이성룡; 이상도; 박영춘

Abstract

Migraine headache is thought to be associated with a dilatation of cranial blood vessels and an accompanying localized sterile inflammatory response. Sumatriptan; a selective agonist of 6-hydroxytryptamine receptors; blocks these phenomena. The efficacyges; loss of cognitive abilities as well as functional autonomy; and emergence of neuropsychiatric features has also helped in defining the "typical" AT) patient and in selecting outcome variables relevant to stage of disease under study. The diagnosis of AD is based on numerous clinical; neuropsychological; neuroradiological; and neurophysiological evaluations; but a define diagnosis can only be established at autopsy or by brain biopsy. The next stage in the diagnosis of AD will be the idenlification of people in the incipient presymptomatic stages; using sensitive and specific biological measures such as high resolution imaging of brain structures; combined wirh relevant neuropsychological tests of memory and language. Because the need for a simple and accurate diagnostic marker is increasing as new dru^ treatments emerge; intensive research to identify diagnostic markers is now in progress. sient.

Key Words: Migraine, Sumatriptan